• CCT196969 effectively inhibits growth and survival of melanoma brain metastasis cells 

      Reigstad, Agathe; Herdlevær, Christina Frantzen; Rigg, Emma Kayleigh; Hoang, Tuyen; Bjørnstad, Ole Vidhammer; Aasen, Synnøve Nymark; Preis, Jasmin; Haan, Claude; Sundstrøm, Terje; Thorsen, Frits (Peer reviewed; Journal article, 2022)
      Melanomas frequently metastasize to the brain. Despite recent progress in the treatment of melanoma brain metastasis, therapy resistance and relapse of disease remain unsolved challenges. CCT196969 is a SRC family kinase ...
    • Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis 

      Aasen, Synnøve Nymark; Espedal, Heidi; Keunen, Olivier; Adamsen, Tom Christian Holm; Bjerkvig, Rolf; Thorsen, Frits (Peer reviewed; Journal article, 2021)
      Brain metastasis (BM) is a major cause of cancer patient morbidity. Clinical magnetic resonance imaging (MRI) and positron emission tomography (PET) represent important resources to assess tumor progression and treatment ...