Browsing Institutt for helse og funksjon by Subject "VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762"
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Lack of functional normalisation of blood vessels following anti-angiogenic therapy in glioblastoma
(Journal article; Peer reviewed, 2017)Neo-angiogenesis represents an important factor for the delivery of oxygen and nutrients to a growing tumour, and is considered to be one of the main pathodiagnostic features of glioblastomas (GBM). Anti-angiogenic therapy ... -
Repurposing 18F-FMISO as a PET tracer for translational imaging of nitroreductase-based gene directed enzyme prodrug therapy
(Peer reviewed; Journal article, 2021)Nitroreductases (NTR) are a family of bacterial enzymes used in gene directed enzyme prodrug therapy (GDEPT) that selectively activate prodrugs containing aromatic nitro groups to exert cytotoxic effects following gene ...