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dc.contributor.authorRen, Xuan
dc.contributor.authorLarsen, Sofus Christian
dc.contributor.authorLauritzen, Lotte
dc.contributor.authorRohde, Jeanett Friis
dc.contributor.authorAndersen, Lars Bo
dc.contributor.authorBugge, Anna
dc.contributor.authorJensen, Britt Wang
dc.contributor.authorSpecht, Ina Olmer
dc.contributor.authorHeitmann, Berit Lilienthal
dc.identifier.citationRen, X., Larsen, S. C., Lauritzen, L., Rohde, J. F., Andersen, L. B., Bugge, A., . . . Heitmann, B. L. (2022). Intake of n-3 LCPUFA and trans-fatty acids is unrelated to development in body mass index and body fat among children. BMC Nutrition, 8:1.en_US
dc.description.abstractBackground The number of children and adolescents with obesity has increased worldwide. Some studies have found an increase in the intake of n-3 long-chain polyunsaturated fatty acid (LCPUFA) to be beneficial for weight and obesity status. The objectives of this study were to examine if intake of trans-fatty acids (TFA) and n-3 LCPUFA at school start was associated with weight and body fat development in the following 3 and 7 years, and if substituting other fats for n-3 LCPUFA in regression models influenced weight and body fat development. Methods A total of 285 children (boys:130, girls:155) were included in this study. Weight, height and skinfold thickness (SF) of children were measured at age 6, 9 and 13 years by trained research personnel. Multivariate linear regression models were used to investigate the associations between n-3 LCPUFA or TFA intake and subsequent changes in body mass index (BMI) or SF. To investigate substitution effects, we constructed regression models including information on n-3 LCPUFA and all other energy given components of the diet, except for the nutrient to be substituted (all other fats and specific subgroups; saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs) and other polyunsaturated fatty acids (PUFAs)). Results No significant associations were observed between intake of TFA or n-3 LCPUFA and changes in BMI and SF. Also, results from regression analysis showed substituting other fats for n-3 LCPUFA did not associate with BMI or SF development. Conclusion The lack of associations between n-3 LCPUFA and TFA and adiposity suggests that fat composition in the diet does not play a major role in obesity development among school-aged children.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titleIntake of n-3 LCPUFA and trans-fatty acids is unrelated to development in body mass index and body fat among childrenen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.rights.holder© The Author(s) 2021.en_US
dc.source.journalBMC Nutritionen_US

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