Characterization of monolithic CMOS pixel sensor chip with ion beams for application in particle computed tomography
Tambave, Ganesh Jagannath; Alme, Johan; Barnaföldi, Gergely Gábor; Barthel, Rene; van den Brink, Anthony; Brons, Stephan; Chaar, Mamdouh; Eikeland, Viljar Nilsen; Genov, Georgi; Grøttvik, Ola Slettevoll; Pettersen, Helge Egil Seime; Pastuović̀, Željko; Huiberts, Simon; Helstrup, Håvard; Hetland, Kristin Fanebust; Mehendale, Shruti Vineet; Meric, Ilker; Malik, Qasim Waheed; Odland, Odd Harald; Papp, Gábor; Peitzmann, Thomas; Piersimoni, Pierluigi; Rehman, Attiq Ur; Reidt, Felix; Richter, Matthias; Røhrich, Dieter; Sudár, András; Samnøy, Andreas Tefre; Seco, Joao Carlos; Shafiee, Hesam; Skjæveland, Eivind Vågslid; Sølie, Jarle Rambo; Ullaland, Kjetil; Varga-Kofarago, Monika; Volz, Lennart; Wagner, Boris; Yang, Shiming
Peer reviewed, Journal article
Published version
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https://hdl.handle.net/11250/2643427Utgivelsesdato
2019Metadata
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Originalversjon
Tambave, G., Alme, J., Barnaföldi, G. G., Barthel, R., van den Brink, A., Brons, S., . . . Yang, S. (2020). Characterization of monolithic CMOS pixel sensor chip with ion beams for application in particle computed tomography. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 958. 10.1016/j.nima.2019.162626Sammendrag
Particle computed tomography (pCT) is an emerging imaging modality that promises to reduce range uncertainty in particle therapy. The Bergen pCT collaboration aims to develop a novel pCT prototype based on the ALPIDE monolithic CMOS sensor. The planned prototype consist of two tracking planes forming a rear tracker and Digital Tracking Calorimeter (DTC). The DTC will be made of a 41 layer ALPIDE-aluminum sandwich structure. To enable data acquisition at clinical particle rates, a large multiplicity of particles will be measured using the highly-granular ALPIDE sensor. In this work, a first characterization of the ALPIDE sensor performance in ion beams is conducted. Particle hits in the ALPIDE sensor result in charge clusters whose size is related to the chip response and the particle energy deposit. Firstly, measurements in a 10 MeV He micro beam have been conducted at the SIRIUS microprobe facility of ANSTO to investigate the dependence of the cluster size on the beam position over the ALPIDE pixel. Here, a variation in cluster size depending on the impinging point of the beam was observed. Additional beam tests were conducted at the Heidelberg Ion-Beam Therapy Center (HIT) investigating the cluster size as a function of the deposited energy by protons and He ions in the sensitive volume of the ALPIDE. Results show the expected increase in cluster sizes with deposited energy and a clear difference in cluster sizes for protons and He ions. As a conclusion, the variation in cluster size with the impinging point of the beam has to be accounted for to enable accurate energy loss reconstruction with the ALPIDE. This does, however, not affect the tracking of particles through the final prototype, as for that only the center-of-mass of the cluster is relevant.