Browsing HVL Open by Author "Gjertsen, Bjørn Tore"

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Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine

Bredholt, Therese; Ersvær, Elisabeth; Erikstein, Bjarte Skoe; Sulen, Andre; Reikvam, Håkon; Aarstad, Hans Jørgen; Johannessen, Anne Chr.; Vintermyr, Olav Karsten; Bruserud, Øystein; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2013)
Modulation of phospho-proteins by interferon-alpha and valproic acid in acute myeloid leukemia

Forthun, Rakel Brendsdal; Hellesøy, Monica; Sulen, Andre; Kopperud, Reidun Kristin; Sjøholt, Gry; Bruserud, Øystein; McCormack, Emmet; Gjertsen, Bjørn Tore (Journal article; Peer reviewed, 2019)

Purpose Valproic acid (VPA) is suggested to be therapeutically beneficial in combination with interferon-alpha (IFNα) in various cancers. Therefore, we examined IFNα and VPA alone and in combinations in selected AML models, ...
p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy

Haaland, Ingvild; Hjelle, Sigrun Margrethe; Reikvam, Håkon; Sulen, André; Ryningen, Anita; Cormack, Emmet Mc; Bruserud, Øystein; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2021)

p53 protein isoform expression has been found to correlate with prognosis and chemotherapy response in acute myeloid leukemia (AML). We aimed to investigate how p53 protein isoforms are modulated during epigenetic ...